CORDIS Project
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This project investigates how transcription factors interact with proteins in eukaryotic cells, focusing on their activation domains and their role in forming transcriptional condensates. By utilizing advanced techniques in yeast, the research aims to clarify the connections between genetic sequences, protein structure…
Transcription factors often serve as key hubs for dynamic protein-protein interactions in eukaryotic cells.
Aside from their characteristic DNA binding domains, the vast majority of transcription factors contain activation domains that are often intrinsically disordered.
These domains are not well-characterized, but are thought to contain key sequence-distributed features that enable transcription factors to interact with their many binding partners, and have recently been associated with the ca…
FUNDACIO CENTRE DE REGULACIO GENOMICA
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