CORDIS Project
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This project explores a novel treatment for Cystic Fibrosis by using healthy lung epithelial cells derived from induced pluripotent stem cells. It aims to correct genetic mutations and transplant these cells to restore lung function.
Cystic Fibrosis is a hereditary disease produced by the absence or malfunctioning of the Cystic Fibrosis Transmembrane Conductase Regulator (CFTR) gene.
To date over 1,200 alterations in the DNA composition of the CFTR gene have been detected, although the deletion of the phenylalanine in position 508 (ΔF508) is responsible for more than 70% of the cases described in the European Population. CF is a degenerative disease, which can be considered as the main genetic cause of death in Caucasian chi…
FOUNDATION HEALTH RESEARCH INSTITUTE OF THE BALEARIC ISLANDS
FUNDACIO INSTITUT D'INVESTIGACIO SANITARIA ILLES BALEARS
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