CORDIS Project
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This project explores the role of specific transcription factors in glioblastoma, a type of brain cancer. It aims to understand how these factors influence stem cell characteristics and tumor growth, potentially leading to new treatment strategies.
Cancer is one of the leading causes of death worldwide.
Brain cancers, in particular glioblastoma (GBM), have incredibly poor prognosis and there are currently few effective treatments.
Our understanding of the molecular defects associated with cancer has significantly increased over the past decade.
Many of the commonly disrupted genes control cell proliferation and survival pathways.
However, it is increasingly clear that genetic changes operate in a tissue-specific and developmental context a…
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