CORDIS Project
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This project aims to enhance a new genome engineering tool based on CRISPR technology, allowing for the simultaneous control of multiple genes. By applying statistical physics, the researcher seeks to improve the tool's efficiency for applications in gene network manipulation and cellular signaling.
In the last 10 years, an increasing number of studies employed -omics technologies to describe the molecular changes underpinning cellular functions.
However, a large part of these findings is awaiting an experimental validation.
This is due to the lack of efficient molecular tools able to control both multiple and distinct genetic interactions.
Recently, I described a new CRISPR/12-based genome engineering tool that, for the first time, it provides the constitutive, conditional, inducible, ort…
POLITECNICO DI TORINO
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