CORDIS Project
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This project focuses on developing new methods to create modified sugars and glycolipids that can help diagnose and treat tuberculosis. By utilizing unique sugar motifs found in the bacteria, the research aims to improve imaging techniques and therapeutic strategies against drug-resistant strains of the disease.
Tuberculosis (TB) is a common and deadly infectious disease caused by mycobacteria, mainly Mycobacterium tuberculosis (MTB).
In the developed world, the advent of powerful antibiotics and a concerted inoculation program saw the near extinction of TB.
However, the rise of drug-resistant strains, HIV infections, and the neglect of TB control programs have increased the urgency for an alternative treatment and diagnosis.
Since the presence of L-rhamnose and trehalose [α-D-Glc-(1↔1)-α-D-Glc] motifs…
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