CORDIS Project
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This project aims to develop glycan-based nanomedicines to enhance immune responses against cancer and infectious diseases. By targeting dendritic cells, the research seeks to improve T-cell activation and create effective vaccine platforms for treating various health conditions.
There is an urgent need to develop vaccines for the induction of CD8+ T-cell immunity to treat cancer and infectious diseases.
Dendritic Cells (DC) have shown potential to induce antigen specific CD8+ T-cell responses with the help of CD4+ T cells, yet the efficacy by which the induction is achieved still has its limitations.
The main challenge is: (a) to increase targeting efficacy to the complete repertoire of DC subsets; (b) to trigger T-cell responses by the DC that is powerful enough to eli…
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Netherlands, Amsterdam
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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