CORDIS Project
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This project focuses on understanding how sugars on cell surfaces interact with viruses, aiming to develop new strategies for combating infections. By chemically modifying glycans on cells, it seeks to reveal their roles in infection processes and improve the design of glycan-based therapies.
Every human cell is covered by a dense coat of glycans (sugars, carbohydrates).
Sugars are the first molecules that viruses encounter when they approach host cells.
Many viruses encode lectins to adhere to the outer glycan layer and start infection.
In this scenario, Glycoscience holds a tremendous potential for combating infections.
Elucidating the molecular basis of infection is essential, but far from trivial.
The complexity of the chemistry of glycans, including synthesis, structure, conform…
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