CORDIS Project
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This project investigates the internalization mechanisms of metabotropic glutamate receptors in brain cells, aiming to clarify their role in neuronal transmission. By utilizing advanced biophysical techniques and nanobodies, the research seeks to enhance understanding of receptor localization and responses to neurotran…
G protein-coupled receptor (GPCR) are membrane proteins targeted by around 30 % of all marketed drugs. GPCR internalization is a mechanism that tunes the cell surface versus intracellular receptor ratio, a parameter that plays an essentiG protein-coupled receptor (GPCR) internalization is a mechanism involved in the tuning of cell surface versus intracellular receptor ratio, a parameter that plays an essential role in controlling receptor physiological responses.
This process is very well descri…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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