CORDIS Project
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This project aims to understand the mechanisms behind glioblastoma, a highly aggressive brain cancer. It focuses on the role of specific genetic factors in tumor development, seeking to identify new therapeutic targets for treatment.
Glioblastoma (GBM) is the most aggressive form of glioma, the most common primary brain cancer in adults. GBM is highly resistant to standard radiotherapy and chemotherapy treatments and thus represents a leading cause of cancer-related death worldwide.
Although many genetic alterations have been identified for GBM, its histogenesis is still poorly understood.
The relative contribution of each genetic alteration and their downstream effects, as well as the sequence of molecular and cellular even…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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