CORDIS Project
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This project addresses the challenge of delivering anti-cancer drugs to solid tumors, particularly glioblastoma. It aims to develop tumor-penetrating peptides that enhance drug delivery to infiltrating cancer cells, potentially improving treatment efficacy.
This application addresses a major problem in therapy of solid tumors: poor penetration of anti-cancer drugs into tumor tissue and to infiltrating tumor cells.
Recently, we have identified tumor penetrating peptides (TPP) that trigger specific penetration of co-administered un-conjugated drugs deep into tumor and increase their therapeutic index.
Current TPP target angiogenic tumor vessels and may not be suitable for targeting slow-growing tumors and invasive tumor cells. TPP are composed of fun…
TARTU ULIKOOL
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