CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the transport mechanisms of leptin, a hormone involved in regulating body weight, across the blood-brain barrier. By studying how this process is altered in obesity, it aims to uncover potential therapeutic targets for treating metabolic disorders.
Metabolic disorders such as obesity and diabetes are age-related diseases, and lead cause of death in Europe.
Adiposity signals such as leptin and insulin, whose circulating levels are in proportion to body fat, convey metabolic information to neural networks that regulate energy homeostasis in the hypothalamus.
In leptin-deficient humans and mice, leptin administration effectively reduces hyperphagia and obesity.
Paradoxically, most cases of obesity display high circulating leptin levels that f…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
