CORDIS Project
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This project investigates the communication between enteric glial cells and macrophages in the gut, focusing on their role in intestinal inflammation and homeostasis. By exploring the molecular mechanisms involved, it aims to identify new therapeutic targets for inflammatory bowel disease.
Uncovering Enteric GLIA-MACrophage communication in the intestinal homeostasis and inflammation.The enteric nervous system (ENS) is a network of neurons and enteric glial cells (EGCs) organized in ganglia essential to control gastrointestinal physiology.
Although EGCs have historically been described as supporting cells for enteric neurons, recent data from my previous work and from my host group demonstrated that enteric glia is “communicating” with innate immune cells via the secretion of immu…
KATHOLIEKE UNIVERSITEIT LEUVEN
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