CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the formation of amyloid fibrils, which are linked to diseases like Alzheimer’s and Parkinson’s. It aims to map mutations affecting amyloid nucleation and develop predictive models for protein aggregation, ultimately guiding therapeutic strategies for amyloid-related diseases.
Amyloid fibrils form and precipitate in more than 50 incurable human diseases, including Alzheimer’s and Parkinson’s disease.
All proteins may be able to form amyloids, at least under certain circumstances.
However, aggregation is actually rare as the process of amyloid formation is controlled by a high kinetic barrier: protein sequences have to cross a free energy barrier to nucleate transition states which then seed irreversible fibril formation.
Short-lived transition states are extremely cha…
FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
Guests see up to 5 keywords.
