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The Give-Me-Five project aims to develop stable fluorinated molecules, particularly focusing on the pentafluorosulfanyl (SF5) motif, which could replace the less stable trifluoromethyl (CF3) group. This research targets applications in agrochemicals, pharmaceuticals, and materials by creating new synthesis methods for…
The Give-Me-Five project will provide the next generation of fluorinated molecules that found plethora of applications in life science.
Currently up to 50% of agrochemicals as well as 20% of pharmaceuticals contain a fluorinated motif.
As an example, the trifluoromethyl (CF3) group is one of the most used fluorinated motifs in research and development.
Although several research programs have been dedicated to the synthesis of CF3-molecules with numerous CF3-reagents being developed, recent repor…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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