CORDIS Project
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This project focuses on developing therapeutic antibodies to neutralize immunogenic gluten peptides for individuals with celiac disease who struggle with a gluten-free diet. By creating improved versions of these antibodies, the project aims to enhance treatment options and diagnostic capabilities for affected patients…
Celiac disease affects about 1% of the population worldwide.
It is an autoimmune disease triggered by gluten intake in genetically predisposed individuals.
Celiac disease causes intestinal villi atrophy that results in a deficient absorption of nutrients and other risks.
Gluten major sources are wheat, rye, barley and some oats.
Currently, the only effective treatment is a permanent gluten free diet (GFD).
However, a fully GFD is difficult to achieve.
The average daily gluten intake in celiac pa…
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