CORDIS Project
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This project investigates the genetic basis of tissue transparency to enhance optical clarity in biological tissues. By employing precision genetics, the aim is to develop methods that allow living cells and tissue cultures to become more transparent, facilitating advanced imaging techniques in various biological appli…
Most biological tissues are optically opaque, largely precluding access by light microscopy.
In stark contrast, some living tissues and organisms are highly transparent.
Examples include many deep-sea fish, your retina, and cells that we exposed to directed evolution.Here we propose to uncover the genetic basis of tissue transparency, such that living cells and tissue cultures can be optically cleared by precision genetics.
For this we will combine insights into origins of retina transparency, a…
KARLSRUHER INSTITUT FUER TECHNOLOGIE
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