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The Ghostbuster project investigates unique neurons in the hypothalamus that can change their identity throughout adulthood. By studying these 'Ghost' neurons, the project aims to understand their role in regulating metabolism and their potential link to disorders like obesity.
The hypothalamus contains heterogeneous neurons that dictate behaviours and physiological functions through cross-talk mechanisms with peripheral hormones.
Neuronal diversity is the key to enabling hypothalamic functions and, according to the neuroscience dogma, is mainly preset during embryonic life.
But what if this model is incorrect?
Can neuronal heterogeneity be plastically modulated throughout adult life as well?
Here, based on my published work and solid preliminary results, I propose tha…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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