CORDIS Project
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This project investigates programmed DNA elimination during the differentiation of germline and somatic cells in zebra finches. By analyzing the germline-restricted chromosome, it aims to understand how this process minimizes genetic conflict between germline and soma, utilizing advanced genomics and developmental tech…
Many multicellular organisms have a division between germline and soma.
It has been long-standing dogma that all these cells have the same genome as they develop from a single cell.
However, programmed DNA elimination can remove DNA during germline–soma differentiation and thereby lead to dramatic differences in genome organization between tissues.
The evolution and function of programmed DNA elimination remains mysterious due to technological limitations and lack of an evolutionary framework. H…
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United Kingdom, Norwich
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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