CORDIS Project
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This project studies the immune synapse, focusing on how the microtubule-organizing center influences communication and transport at the contact site between T cells and antigen-presenting cells. It aims to understand RNA transfer during immune responses.
Cell-cell synapses are an exquisitely evolved means of communication between cells.
During the formation of the immune synapse (IS), diverse transmembrane and membrane associated molecules are reorganized into a highly segregated structure at the T cell–Antigen-Presenting Cell (APC) contact site.
As part of this process, the tubulin cytoskeleton is vectorially directed toward the center of the IS, where the microtubule-organizing center (MTOC) localizes. MTOC translocation is an early event in I…
CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.)
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Spain, Madrid
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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