CORDIS Project
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This project investigates the genetic factors contributing to thoracic aortic aneurysm and dissection. It aims to identify genetic modifiers that influence disease severity, enhancing understanding and treatment of this serious condition.
Thoracic aortic aneurysm and dissection (TAAD) is an important cause of morbidity and mortality in the western world.
As 20% of all affected individuals have a positive family history, the genetic contribution to the development of TAAD is significant.
Over the last decade dozens of genes were identified underlying syndromic and non-syndromic forms of TAAD.
Although mutations in these disease culprits do not yet explain all cases, their identification and functional characterization were essenti…
UNIVERSITEIT ANTWERPEN
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