CORDIS Project
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This project focuses on recovering and analyzing ancient DNA sequences from E. coli to understand evolutionary biology. By comparing ancient strains with modern genomes, it aims to reveal insights into adaptation mechanisms and the historical prevalence of virulence factors linked to foodborne illnesses.
The retrieval of ancient DNA sequences from long-dead organisms offers a unique perspective on evolutionary biology.
In this proposal, we aim to take advantage of cutting-edge approaches in next-generation sequencing, together with the contributions of other fields, including medicine, experimental biology and microbiology, in order to access the complete genome sequences of ancient E. coli organisms that lived several hundreds to thousands of years ago. DNA enrichment coupled with high-throughp…
KOBENHAVNS UNIVERSITET
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