CORDIS Project
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This project aims to develop a computational strategy to identify drug targets for glioblastoma multiforme, a severe brain cancer. By leveraging polypharmacology and protein domain structures, the project seeks to reposition existing drugs for effective treatment.
This project will establish a computational strategy which exploits polypharmacology to identify drug targets in biological systems implicated in cancer.
The value of our polyphamacology platform will be tested by application to glioblastoma multiforme, a deadly brain cancer.
The aim will be to identify multiple targets in protein networks linked to glioblastoma to thereby enable repositioning of drugs against that cancer.
The novelty of the work will lie in its use of protein domain structure d…
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