CORDIS Project
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This project investigates the genetic factors influencing biological age and longevity using Asian elephants as a model. By analyzing a century-long dataset on elephant life history and health, the research aims to uncover insights into the genetic architecture of ageing relevant to humans.
European populations are ageing, and this has important health, economic and social consequences.
Yet in order to manage these, we need to understand the complex phenomenon of ""biological age"", and in particular its genetic determinants.
It is now established that longevity insurance genes such as TP53 mitigate the roles of mitochondrial function, oxidative stress and telomere shortening, and that these genes are also involved in ageing, with senescence and cancer being two faces of the cell g…
TURUN YLIOPISTO
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