CORDIS Project
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This project investigates how GABAergic interneurons influence the synchronization of neuronal activity in the hippocampus, particularly focusing on theta oscillations and their role in spatial memory. By manipulating these interneurons in specific regions, the research aims to understand their impact on network activi…
GABAergic interneurones can effectively synchronize the activity of principal cells giving rise to distinct oscillatory patterns. A particular rhythm, hippocampal theta oscillations (6-10Hz), links two ways of coding by which pyramidal cells in the hippocampus represent space, namely rate and phase coding.
Thus, the theta cycle provides a clock against which the increased firing rate of pyramidal cells in the hippocampus and entorhinal cortex is measured.
Furthermore, hippocampal theta is believ…
UNIVERSITATSKLINIKUM HEIDELBERG
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