CORDIS Project
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This project focuses on the dynamics of G-quadruplex DNA at telomeres using advanced optical techniques. By studying how these structures behave in live cells, the research aims to improve understanding of their biological functions and potential implications for cancer therapies.
Telomeres, the ends of linear eukaryotic chromosomes, are one of the most versatile “molecular machines” of life.
They perform a vital role in several fundamental processes in biology, as maintenance of genome integrity and the regulation of cell growth.
Human telomeric DNA consists of thousands of tandem repeats of guanine-rich sequences, terminating the chromosomes.
Under physiological conditions, such guanine-rich repeats are capable of adopting four stranded structures, called G-quadruplex D…
AARHUS UNIVERSITET
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