CORDIS Project
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This project aims to develop new vaccine adjuvants that enhance immune responses more effectively than traditional methods. By leveraging recent insights into the innate immune system, it seeks to create compound adjuvants that stimulate multiple immune pathways, improving vaccine efficacy and safety.
New vaccine modalities need to be developed that can activate more potently the immune system, in this regard, adjuvants augment adaptive immune responses and can improve vaccine performance.
Aluminium salt (alum) is the most commonly used adjuvant for human vaccination.
However, it drives primarily TH2-effector responses and is not effective for vaccines that target mucosal surfaces.
Thus, safe and potent adjuvants need to be developed that can increase and direct vaccine-specific immunity.
Rec…
UNIVERSITEIT UTRECHT
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