CORDIS Project
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This project aims to understand the molecular basis of fungal pathogenicity, particularly in bloodstream infections. By integrating molecular data with physiological contexts, it seeks to identify traits that differentiate pathogenic from non-pathogenic fungi.
Fungal infections pose a serious medical threat, especially when they invade the bloodstream.
The most common cause of fungal bloodstream infections is invasive candidemia, primarily attributed to a small group of pathogens, including Candida albicans, Nakaseomyces glabratus, Candida tropicalis, and Candida parapsilosis.
Such infections are associated with crude mortality rates nearing 40%.
Increasing numbers of very closely related yet non-pathogenic species have been sequenced and identified.…
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