CORDIS Project
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This study investigates antifungal resistance in the pathogen Aspergillus fumigatus, focusing on how cell heterogeneity affects treatment outcomes. It employs advanced techniques to analyze cell types and their resistance mechanisms, aiming to inform new antifungal therapies.
The number of people who die from fungal infections is estimated to be equivalent to or greater than the numbers that die from either tuberculosis or malaria.
There are only 3 classes of antifungal drugs available to treat these invasive diseases and resistance against these drugs is increasing.
In this study I will investigate how antifungal resistance is impacted by cell heterogeneity in the pathogenic fungus Aspergillus fumigatus.
The main hypothesis that I will test is that fungal cell heter…
THE UNIVERSITY OF MANCHESTER
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