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The FunDiT project investigates the diversity of CD8+ T cell subsets and their roles in immune responses. By identifying these subsets and their functions, the project aims to enhance understanding of adaptive immunity in various disease contexts.
T cells have a central role in most adaptive immune responses, including immunity to infection, cancer, and autoimmunity.
Increasing evidence shows that even resting steady-state T cells form many different subsets with unique functions.
Variable level of self-reactivity and previous antigenic exposure are most likely two major determinants of the T-cell diversity.
However, the number, identity, and biological function of steady-state T-cell subsets are still very incompletely understood.
Recept…
UMG INSTITUTE OF MOLECULAR GENETICS ACA SCIEN CZECH REPU
USTAV MOLEKULARNI GENETIKY AV CR V.V.I.
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