CORDIS Project
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This project aims to develop Functional Biomarkers as diagnostic tools for managing chronic diseases, focusing on the role of X-prolyl dipeptidylpeptidases in patient treatment. It seeks to create in vitro diagnostic tests that can predict treatment outcomes for chronic hepatitis C patients and potentially other diseas…
The aim of this proposal is to establish a business plan for the development of a new class of Functional Biomarkers as in vitro diagnostic tools for managing patients with chronic disease.
The proof of concept will be established by focusing on substrates of the X-prolyl dipeptidylpeptidases (DPP), a family of pleotropic enzymes that cleave the N-terminal two amino acids of proteins.
There are >30 known substrates for DPPIV, the best characterized member of this family.
Importantly the catalyti…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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