CORDIS Project
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This research focuses on understanding the role of macrophages in Type 1 diabetes, particularly their interaction with T cells that damage pancreatic beta cells. It aims to explore the immune mechanisms involved in the disease's progression and potential therapeutic approaches.
Type 1 diabetes (T1D) is a chronic condition that results from the specific destruction of pancreatic beta cells by the immune system.
As a consequence, affected individuals can no longer regulate their blood sugar levels and become dependent on glucose monitoring and insulin injections.
Despite careful disease management, serious neuronal and vascular long-term complications can often not be avoided.
This debilitating disease is an important and growing public health concern in Europe: it is pr…
UNIVERSITEIT GENT
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