CORDIS Project
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This project investigates the energy requirements of fibroblastic reticular cells in lymphoid organs, focusing on how their metabolism influences immune responses during inflammation. By understanding these mechanisms, the research aims to enhance immunotherapy strategies for infections, cancer, and autoimmune diseases…
Induction and regulation of optimal immune responses depends on the proper functioning of fibroblastic reticular cells (FRCs) of secondary lymphoid organs (SLOs).
Energy balance maintained through the choice of ideal metabolic pathways critically influences the performance of immune cells.
Currently, the bioenergetic demands of FRCs and how they impinge on their function remain elusive.
The overarching goal of this project is to decipher the bioenergetic needs of FRCs in homeostasis and during i…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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