CORDIS Project
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This project explores the role of specific proteins in regulating autophagy, a critical cellular process for maintaining tissue health. By investigating the interactions of these proteins, it aims to uncover mechanisms that could lead to therapeutic strategies for diseases like cancer and neurodegeneration.
Autophagy is a conserved, highly regulated degradative pathway transferring cytoplasmic components in autophagosomes to lysosomes providing energy for cellular metabolism.
In multicellular organisms autophagy is essential for tissue homeostasis and deficient autophagy is implicated in a broad range of diseases e.g. cancer and neurodegenerative disorders.
To develop therapeutic strategies targeting autophagy a comprehensive understanding of the molecular protein machinery mediating and regulating…
CANCER RESEARCH UK LBG
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