CORDIS Project
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This project investigates calcium signaling in the photoreceptors of fruit flies, focusing on how it affects light detection. The research aims to understand the feedback mechanisms involved in phototransduction and their implications for vision.
A major challenge for any visual system is the dramatic difference in ambient light between a starlit night and midday sun.
In contrast to the ciliary rods of vertebrates, the rhabdomeric photoreceptors of the common fruitfly not only reliably detect single photons when dark-adapted (generating responses called ‘quantum bumps’), but continue responding in full daylight.
At the core of this performance lie positive and negative feedback loops, many involving Ca2+ entry through the light activated…
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