CORDIS Project
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This project aims to understand how influenza viruses evade immune responses by manipulating autophagy, a cellular process crucial for antigen processing. It investigates the molecular interactions of viral proteins with autophagy machinery to improve vaccine strategies against influenza.
Influenza infections kill around 300.000 people each year.
Due to its ability to reassort with viruses from other animal species and its mutational drift, society is in great need of novel vaccination strategies.
Autophagy is involved in the delivery and processing of antigens derived from different viruses.
Influenza and other viruses often target this important mechanism to evade immune recognition.Here, I aim at unraveling the molecular mechanisms underlying the fusion of autophagosomes with…
University of Zurich
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