CORDIS Project
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This research investigates the role of alveolar macrophages in the early response to influenza infections. It aims to understand how these immune cells contribute to viral replication and the body's inflammatory response, with implications for improving influenza treatment and prevention.
Influenza viruses are among the most common causes of respiratory infections in humans, and are associated with high morbidity and mortality.
Lung or alveolar macrophages (AM) are among the first cells to react to influenza A challenge, and their activation causes increased phagocytosis and production of numerous proinflammatory cytokines.
Targeting of the AM by incoming influenza virus may be important because of the macrophage role in limiting viral replication and in the immune response to vi…
THE UNIVERSITY OF EDINBURGH
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