CORDIS Project
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This project explores the interactions of neurotropic flaviviruses, such as Zika and tick-borne encephalitis viruses, with their hosts. It aims to understand how these viruses adapt and spread in humans and arthropods by studying their RNA interactions and the immune response, which could inform future therapeutic stra…
Neurotropic flaviviruses Zika virus (ZIKV) and tick-borne encephalitis (TBEV) represent major emerging arthropod-borne viruses transmitted by two different vectors, either mosquitoes or ticks.
In humans, they use cells of the immune system to spread throughout the organism and can lead to severe encephalitis.
During their replication, viruses produce double-stranded RNA (dsRNA) structures which is not only a necessary by-product but also performs key regulatory functions and acts as a pathogen-a…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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