CORDIS Project
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This project investigates how populations adapt to new environments by studying genetic interactions and their effects on adaptation. It employs experimental evolution to explore fitness landscapes and predict drug resistance in pathogens.
A major challenge in evolutionary biology is to quantify the processes and mechanisms by which populations adapt to new environments.
In particular, the role of epistasis, which is the genetic-background dependent effect of mutations, and the constraints it imposes on adaptation, has been contentious for decades.
This question can be approached using the concept of a fitness landscape: a map of genotypes or phenotypes to fitness, which dictates the dynamics and the possible paths towards increas…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Portugal, Lisboa
Type: Research institute
Activity type: Research Organisations
SME: No
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