CORDIS Project
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This project explores the role of non-coding regions in the genome, particularly in blood cancers. It aims to understand how these regions influence gene expression and drug resistance, potentially leading to new therapeutic strategies for conditions like Chronic Myelogenous Leukemia.
Functional non-coding regions of the genome play a fundamental role in gene expression and are enriched for disease associated variants.
Perturbation of non-coding regions harbouring disease-associated variants is now the rationale of ongoing clinical trials (e.g. NCT03432364), highlighting the translational potential of basic research in the non-coding space.
However, our ability to systematically identify disease-associated functional elements in the non-coding genome, understand its grammar,…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Austria, Wien
Type: Research institute
Activity type: Research Organisations
SME: No
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