CORDIS Project
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This project aims to generate adult intestinal stem cells from human induced pluripotent stem cells in controlled laboratory conditions. It focuses on understanding the molecular mechanisms that drive the maturation of these stem cells, which is crucial for developing transplantation therapies and modeling neonatal dis…
One of the challenges in regenerative medicine is to generate adult intestinal stem cells (ISCs) from human induced pluripotent stem cells (hiPSC) in vitro in defined conditions.
This will be important in order to establish intestinal cell transplantation therapies and a platform for neonatal disease modelling.
These issues constitute the main goal of the proposal.
The current protocols to direct intestinal differentiation from hiPSC impede their suitability for human transplantation purposes ei…
KOBENHAVNS UNIVERSITET
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