CORDIS Project
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This project focuses on the development of skeletal and cardiac muscles during pregnancy, investigating congenital diseases linked to muscle function. It aims to enhance understanding of myosin isoforms and their regulatory mechanisms in foetal muscle development.
In utero development is critical for normal skeletal and cardiac muscle function throughout life.
Many diseases, such as distal arthrogryposis (affecting 1/3000 live births) and clubfoot (1/1000) in skeletal muscle and arrhythmias in cardiac muscle (1/4000), manifest in the embryonic and foetal period.
They permanently affect longevity and quality of life.
Because the effects of these diseases are present at birth, the study of in utero samples is essential to understanding the diseases’ proper…
UNIVERSITY OF KENT
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