CORDIS Project
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This project investigates the genetic factors involved in epilepsy, particularly focusing on the regulatory elements of genes in the developing forebrain. By utilizing advanced techniques, it aims to identify mutations that disrupt gene regulatory networks, potentially leading to new insights into neurodevelopmental di…
The human forebrain plays critical roles in cognition, motor function, and emotion.
Impaired forebrain development and function are associated with neurodevelopmental disorders, including epilepsy.Early onset of epilepsy is a spectrum of disorders with strong genetic components that could be difficult to precisely diagnose and provide effective treatments. A major and underexplored cause of complex disorders could be mutations in gene regulatory elements.
For example, disruption of these element…
BEN-GURION UNIVERSITY OF THE NEGEV
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