CORDIS Project
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This research investigates the unique properties of human neurons that contribute to cognitive functions. By exploring fast-processing neuron types and their synaptic networks, the project aims to uncover mechanisms that underlie human cognition and their implications for brain disorders.
How human neuronal circuits are organized to produce human cognition is poorly understood.
We recently showed (Nature, 2021) that human neocortex contains neuron types not found in other mammals.
My preliminary data show that large, human-specialized transcriptomically-defined cell types (t-types) have surprisingly fast processing of synaptic input to action potential output properties.
Other human t-types show much slower input-output properties more akin to average mammalian neurons.
These fas…
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