CORDIS Project
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This project aims to improve pancreatic islet transplantation for diabetes treatment by using genetically engineered islet organoids in the anterior chamber of the eye. The goal is to enhance islet survival and enable non-invasive monitoring of their function.
Pancreatic islet transplantation is essential for diabetes treatment.
Outcome varies due to transplantation site, quality of islets and the fact that transplanted islets are affected by the same challenges as in situ islets.
Tailor-making islets for transplantation by tissue engineering combined with a more favorable transplantation site that allows for both monitoring and local modulation of islet cells is thus instrumental.
We have established the anterior chamber of the eye (ACE) as a favorab…
KAROLINSKA INSTITUTET
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