CORDIS Project
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This project explores how intestinal infections affect the glycosylation profile of glycoproteins in the intestine. By identifying specific glycosyltransferases involved in this process, the research aims to understand the molecular changes triggered by infections.
Cellular Glycosylation is a finely tuned process that is very suscpetible in changes due to environmental stimuli.
We have preliminary data showing that intestinal infections in mice and rats are capable in changing the glycosylation profile of intestinal glycoproteins.
We speculate that this could be due to a translational regulation of glycosyltransferases.
Hence, we would like to use RT-PCR and quantiative proteomic to identify specific glycosyltransferases affected by the infection cycle.
UGOT - GOETEBORGS UNIVERSITET/UNIVERSITY OF GOTHENBURG
GOETEBORGS UNIVERSITET
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Ireland, Galway
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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