CORDIS Project
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The ExpandTILs project aims to enhance cancer immunotherapy by selectively amplifying tumor-reactive lymphocytes from patients. By using reprogrammed cancer cells, it seeks to improve the effectiveness of treatments against solid tumors.
Cancer affects 2.6 million people each year in the European Union, making it the second leading cause of death.
Immunotherapies have revolutionized the treatment of cancer, seeking to re-arm immune cells against tumors.
However, current immunotherapies are mostly inefficient in low immunogenic and solid tumors, which account for more than 80% of cancers in adults. A promising approach is to collect tumor infiltrating lymphocytes (TILs) from patient’s resected tumor tissue, and expand their funct…
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