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The ExoDevo project investigates the role of extracellular vesicles in brain development, focusing on their influence in communication between progenitor cells, neurons, and astrocytes. By utilizing human cerebral organoids, the project aims to uncover mechanisms of cellular cross-talk that may be altered in neurodevel…
Cellular cross-talk is an essential process influenced by numerous factors including secreted vesicles that transfer nucleic acids, lipids, and proteins between cells.
Extracellular vesicles (EVs) have been the center of many studies focusing on neuron-to-neuron communication while the role of EVs in progenitor-to-neuron and -astrocyte communication occurring during brain development has not been systematically investigated.
Extracellular signals regulating the development of the brain are key p…
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
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