CORDIS Project
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This project seeks to develop new therapeutic strategies for Ewing sarcoma, a childhood cancer, by targeting the unique onco-protein responsible for the disease. It aims to create a genetic model to study tumor mechanisms and identify druggable targets.
Development of efficient therapeutic strategies in the past years has drastically reduced the lethality of several common types of pediatric and juvenile form of cancer such as leukemia, lymphoma and brain tumors.
Such a tremendous success, however, does not include sarcomas treatment, whose mortality rate remains the same as twenty years ago.
Ewing sarcoma is a childhood cancer with a relatively low incidence, with 3 cases/million/year.
The initial oncogenic event is represented by a balanced c…
UNIVERSITA DEGLI STUDI DI TRENTO
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