CORDIS Project
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This project aims to explore the evolution of vertebrate regulatory genomic architecture by profiling the genome of the European amphioxus. It seeks to understand how changes in chromatin structures influence gene expression and the development of animal body plans.
Evolution of animal forms largely depends on changes in developmental gene expression patterns.
These genes are controlled by a large number of cis-regulatory elements (CREs) distributed in extended genomic regions organized in 3D chromatin structures known as regulatory landscapes (RLs).
However, it is currently unknown how these RLs originate and evolve and how changes in RL architecture and associated CREs have impacted the evolution of gene expression and animal body plans.
The aim of this p…
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
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