CORDIS Project
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This project investigates the evolution of pregnancy by studying gene regulatory networks in the endometrium. It aims to understand how specific genes contribute to placental development and maternal tolerance of the fetus, providing insights into reproductive health.
One of the deepest unanswered biological questions is how new phenotypes arise in evolution.
To address this question, I propose to investigate a major mammalian innovation: pregnancy.
Phenotypic novelties of pregnancy include efficient placental delivery of nutrients and internal fetal development.
When being established, these novelties were associated with major gene regulatory changes in the endometrium of the uterus.
My preliminary studies in human endometrial cells suggest that aryl hydroc…
TURUN YLIOPISTO
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